Abstract:

 Objective To evaluate the effect of ciliary body on the pathogenesis of acute angle-closure glaucoma by observing the change of the shape and position of ciliary body before and after the acute attack of angle-closure glaucoma. Design Prospective comparative case series. Participants 30 patients with primary acute angle-closure glaucoma admitted to Handan Eye Hospital (the third hospital of handan city) from December 2016 to December 2017. Methods Ultrasound biomicroscopy (UBM) and intraocular pressure (IOP) were performed at the acute attack, 1 month and 6 months after the acute episode of glaucoma. The parameters of ciliary body in UBM images were measured and analyzed by measuring software. Main Outcome Measures Central anterior chamber depth (ACD), maximum ciliary body thickness (CBTmax), ciliary body thickness at the scleral spur (CBT0), ciliary body thickness at 1 mm posterior to the scleral spur (CBT1), anterior placement of the ciliary body，(APCB), trabecular-ciliary process distance (TCPD), iris-ciliary processes distance(ICPD), trabecular meshwork-ciliary process angle（TCA）, trabecular meshwork-iris angle(TIA). Results Compared with the fellow eyes, ACD (1.73, 196 mm), CBTmax (1.07, 1.16 μm), CBT0 (0.90, 0.98 μm) and TIA (1.73, 7.12 degree) in acute attack eyes presented statistical differences (all P<0.05). There were statistically significant differences in ACD, CBTmax, CBT0, APCB, ICPD, TCA, and TIA (all P<0.05) between the acute attack eye and the first month after remission, and there were statistically significant differences in ACD, APCB, TCA, and TIA between the acute attack eye and the six months after remission, but the differences were variant. Conclusion Compared with the fellow eyes and the remission eyes, the acute attack eyes of primary angle-closure glaucoma showed the anatomical features of shallow anterior chamber, narrow angle, thin ciliary body and forward relative position. (Ophthalmol CHN, 2019, 28: 29-33)

Key words:  primary acute angle-closure glaucoma, ciliary body, ultrasound biomicroscopy